General Western Blot Reagents
Abcam Curcumin (Diferuloylmethane), Lipoo x ygenase inhibitor, 250MG
MW 368.4 Da. High purity flavonoid derivative. Potent antioxidant, anti-inflammatory, analgesic and anticancer agent. Lipooxygenase and cyclooxygenase inhibitor (IC₅₀ values are 8 and 52 μM, respectively). Shows diverse range of actions including free radical scavenging activity, cardio and neuroprotective effects. Blood brain barrier permeable. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human non-muscle Myosin IIA peptide, 1MG
Human non-muscle Myosin IIA peptide is a Synthetic blocking peptide. >70% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: Myosin-9, Myosin heavy chain 9, Non-muscle myosin heavy chain A, Non-muscle myosin heavy chain IIa, NMMHC-A, NMMHC II-a, NMMHC-IIA, MYH9
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam Isradipine, L-type Ca2+ channel blocker, 10MG
MW 371.4 Da, Purity >98%. L-type Ca2+ channel blocker. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Caged MK 801, NMDA receptor open-channel blocker, 50MG
MW 460.49 g/mol, Purity >99%. Caged, potent, selective, non-competitive, irreversible NMDA receptor open-channel blocker. UV-active MK 801 (ab144485, ab120027, ab120028) analog. Shows anticonvulsant effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Ibotenic acid (mM/ml), e x citoto x ic agonist, 10MM_ML
MW 158.11 Da, Purity >98%. Neuroexcitatory amino acid originally isolated from Amanita species. Neurotoxin often used to model cognitive dysfunctions. NMDA and metabotropic receptor agonist.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human Histone H2B peptide, 1MG
Human Histone H2B peptide is a Synthetic blocking peptide. >90% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: H2BFS, H2BS1, H2BC12L, Histone H2B type F-S, H2B-clustered histone 12 like, H2B.S histone 1, Histone H2B.s, H2B/s
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-P-PDOT, MT2 selective melatonin receptor antagonist, 50MG
MW 279.4 Da, Purity >99%. MT2 selective melatonin receptor antagonist (Ki values are 0.46 and 56 nM for MT2 and MT1 respectively). Counteracts melatonin-mediated ERK- and Nrf2-related antioxidant potential *in vivo.* Centrally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Carbo x y-DCFDA N-succinimidyl ester, Fluorogenic esterase substrate, 50MG
MW 626.35 g/mol, Purity >96%. Cell-permeable, fluorogenic esterase substrate. Becomes hydrolyzed intracellularly to green fluorophore DCFA (ab145439) and covalently bonds to proteins.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Fura-2 K+ salt, fluorescent Ca2+ binding dye, 1MG
MW 832 Da, Purity >95%. Fluorescent Ca2+ binding dye. Binds to Ca2+ with high affinity (Kd = 225 nM in cytosol). Fluoresces green and fluorescence intensity increases upon Ca2+ binding. Cell membrane impermeable. Excitation = 340/380 nm. Emission = 505 nm.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human NRG1 type III peptide, 1MG
Human NRG1 type III peptide is a Synthetic blocking peptide. Suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: GGF, HGL, HRGA, NDF, SMDF, NRG1, Pro-NRG1
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam Chetomin, HIF signaling inhibitor, 5MG
MW 710.9 Da, Purity >98%. Potent HIF signaling inhibitor. Reduces CA9 and VEGF expression in hypoxic cells (IC₅₀ = 10 nM, secreted VEGF, Hep38 cells). Shows antibacterial and antifungal effects. Shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam MeIQ x , Mutagenic agent, 25MG
MW 213.24 Da, Purity >95%. Mutagenic agent. Induces DNA adduct formation. Shows carcinogenic effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam L-Mimosine, non-protein amino acid, 50MG
MW 198.18 g/mol, Purity >98%. Toxic non-protein amino acid originally isolated from Mimosa pudica. Arrests the cell cycle at the G1 phase in PC-3 cells and at the S phase in LNCaP cells, thus attenuating cell proliferation. Blocks cell cycle progression by chelating iron in asynchronous MDA-MB-453 human breast cancer cells. Arrests DNA synthesis by inhibiting deoxyribonucleotide metabolism. Prolyl hydroxylase (PHD) inhibitor stimulating VEGF production, and increasing proangiogenic capacity in dental pulp-derived cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Thymol, phenolic disinfectant, 25G
MW 150.22 g/mol, Purity >98%. Phenolic compound, originally obtained from thyme oil, that is used to inhibit oral bacteria. Also used as a cosmetic biocide/preservative and/or fragrance ingredient. Functions as a denaturant and fragrance ingredient in cosmetic formulations.
The product is subject to the following: Abcam Restricted Use Statement
Abcam TEMPO, stable nitro x yl radical, 500MG
MW 156.25 g/mol, Purity >98%. Widely used as a radical trap, as a structural probe for biological systems in conjunction with electron spin resonance spectroscopy and as a catalyst for the oxidation of primary alcohols to aldehydes. TEMPO-mediated oxidation has been used for the carboxylation of water-resistant nanofibrillated cellulose (NFC) films.
The product is subject to the following: Abcam Restricted Use Statement